E-POSTER DETAIL | 11th Asia Pacific Tele Ophthalmology Society Symposium

Title
Advances in Contact Lenses for Color Vision Deficiency Correction: From Organic Dyes to Plasmonic Nanomaterials

Authors
Wenbo Zhuang, Haidong Zou

Presenting
Wenbo Zhuang

PURPOSE:
To systematically evaluate the technological evolution of filtering materials in contact lenses for color vision deficiency (CVD) management, focusing on the critical transition from traditional organic dyes to localized surface plasmon resonance (LSPR) nanomaterials.

METHODS:
A comprehensive analysis of recent literature was conducted. We evaluated various filtering strategies based on organic dyes and LSPR nanomaterials, assessing their spectral tunability, biocompatibility, and stability within the ocular microenvironment.

RESULTS:
Organic dyes provide effective spectral notching but are fundamentally limited by fixed molecular orbitals and long-term leakage risks. Conversely, LSPR nanomaterials offer exceptional personalized spectral tunability through the modulation of nanoparticle parameters and structural engineering. However, the introduction of rigid metallic nanoparticles disrupts the continuous soft hydrogel network. This mechanical mismatch inevitably increases the lens's elastic modulus and decreases water content, posing clinical risks for long-term wear safety.

RESULTS:

Organic dyes provide effective spectral notching but are fundamentally limited by fixed molecular orbitals and long-term leakage risks. Conversely, LSPR nanomaterials offer exceptional personalized spectral tunability through the modulation of nanoparticle parameters and structural engineering. However, the introduction of rigid metallic nanoparticles disrupts the continuous soft hydrogel network. This mechanical mismatch inevitably increases the lens's elastic modulus and decreases water content, posing clinical risks for long-term wear safety.

CONCLUSIONS:
LSPR nanomaterials have significantly expanded the boundaries of optical tunability for CVD correction. Future development of CVD-correcting contact lenses will move beyond simple material doping, advancing toward a deep intersection of materials chemistry, optical engineering, and advanced manufacturing technologies, ultimately aiming to create personalized visual aids that balance precise spectral reshaping with long-term wear safety.

CONCLUSIONS:

LSPR nanomaterials have significantly expanded the boundaries of optical tunability for CVD correction. Future development of CVD-correcting contact lenses will move beyond simple material doping, advancing toward a deep intersection of materials chemistry, optical engineering, and advanced manufacturing technologies, ultimately aiming to create personalized visual aids that balance precise spectral reshaping with long-term wear safety.